SIM- 34202

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SIM-34202 - Males and Females, 19 - 60

Information file

19 - 60
Smoking habits
Smoker or non-smoker

Body Mass Index (BMI)

Return Visits


Simbec Research Ltd will soon be running a study to investigate 2 e-cigarette devices in comparison with a conventional cigarette. 

This study will be investigating the levels of nicotine in the bloodstream after using each e-cigarette device and after smoking a normal cigarette. The 2 devices to be investigated in this study will be the Vype ePen 2 and the Vype ePen 3, both manufactured by Nicoventures Trading Limited, an affiliate company of British American Tobacco (Investments) Limited (the sponsor of this study). Each device will be tested with different types of e-liquid containing different concentrations of nicotine and different flavouring. You will use all of the different e-liquids, both e-cigarette devices and the conventional Benson & Hedges Skyblue cigarette. 

The purpose of this is to investigate how each variation (e-cigarette device and e-liquid) affects the levels of nicotine in the bloodstream when compared with a normal cigarette and how each product variation affects the satisfaction of the product for the user

The study will consist of a screening visit (approximately 28 days before the start of the study), a treatment visit (approximately 9 days in duration; 8 overnight stays at Simbec, based in Merthyr Tydfil) and a follow up telephone call 5-7 days after your last product use. 

Blood and urine samples will be collected at various timepoints during your stay at Simbec to monitor your safety and to assess the levels of nicotine in your blood following each product use. 

If you experience some side effects that require any medical follow up, you may be asked to attend Simbec for a visit with a study doctor. I have enclosed a sheet with the proposed study dates and times for your information. 


If you complete this study, you will receive a maximum inconvenience payment  of £2000. 

Please note that when you attend for a pre-study screen/medical you will be required to attend the screening visit 'fasted' (you should not have eaten anything for at least 4 hours). We also advise you not to eat any food containing poppy or sesame seeds (such as bread rolls) for 3 days before you attend the screening visit or take part in any strenuous exercise for 7 days before you attend, and not to drink any alcohol for 2 days before you attend the screening visit as these can affect your results and may prevent you from taking part in the study.   


It is also important that you bring your usual e-cigarette device and cigarettes that you use on a daily basis to your screening visit.  




Other available studies

males females SIM-33575 (Smoker) Age 23 - 55 Compensation Up to £3500
males females SIM-33322 (Non / Ex-smoker only) Age 18 - 55 Compensation £2500

Please note

Study dates and availability may change at any time. There is no guarantee that these studies will still be available or that the dates will be the same when you contact our call centre. We do our best to ensure that the information published is up-to-date.

Information about the medication involved in the study is not provided on this Web site to respect the industry confidentiality. For more information about a specific study, please contact one of our call centre agents at 0800 691995.

Please note that during the in-house portion of the study you are expected to remain at our clinic throughout the entire duration of the stay. Although you are free to withdraw your participation at any time during the study, leaving the premises before the end of the intended stay, will result in the termination of your participation in the study.

Give us a call

Simply contact one of our recruitment staff who will be happy to take you through the initial process of joining our panel of volunteers.

0800 691995

By e-mail