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Why do we need to conduct clinical trials?

The majority of us at sometime in our lives have or will have been prescribed some form of medication by our doctor. These medications are developed using clinical trials, so each time we use a medication, we benefit directly from these clinical trials which have involved healthy participants just like you.

Medicines we now take for granted, such as Ibuprofen and antibiotics like amoxicillin were once new drugs and had to undergo a series of Clinical Trials before being allowed onto the market. In fact, these medicines continue to be researched as pharmaceutical companies strive to improvements in their formulation.  

Giving a medicine to a healthy participant provides information on the safety and tolerance of new medicines and how a healthy body absorbs and excretes drugs. This can be tested, for example, by taking blood and urine samples, measuring blood pressure and performing an ECG (a trace of your heart rate) at various times in the day.

Have you ever considered how a doctor knows how frequently you need to take a drug? Again, this information is obtained from measuring the drug in participants' blood. This is done by taking blood samples over a period of time and then measuring the amount of drug in each sample.

What are the benefits of volunteering to take part in clinical research?
  • You may help in the development of medicines that may help someone suffering from a chronic, serious or life-threatening illness.
  • You may provide important scientific information for developing the medicines of the future.
  • You'll receive a thorough medical examination and blood screen to check your health status.
  • Participants who take part in clinical research studies at Simbec receive a generous inconvenience payment which can range from £300 to £7,000.
  • Whilst on a study you'll have lots of time to relax, catch up on some studying using our free Internet access, chill out in the reading room, play pool or test your knowledge and skill by playing our board games.
  • Simbec will provide all your meals during your stay as well as provide transport to and from Simbec whilst on a study
Is it safe and are there any side effects?

Have you ever read the information on a box of pills? If so, you’ve probably seen that most medicines have potential side effects. As a participant it is natural that you will be concerned about your safety. That is why here at Simbec the wellbeing of our participants is our top priority. Each and every study we undertake is submitted to the South East Wales Research Ethics Committee, who as an independent group, reviews the information available and ensures that each study maintains the highest levels of safety before allowing it to proceed.

What does a typical trial involve?

Before the start of every trial, you will have to undergo a pre-trial medical examination and blood test to ensure that you are suitable to take part. Before this medical examination, you will be provided with the full trial details and will be asked to sign a consent form. If you decide to take part in a trial and require transport to Simbec, we will arrange this for you.

Every trial follows a strict schedule of events. For example you may need to fast overnight in preparation for the dosing of the trial medication, which usually occurs in the morning. Dosing is mostly in tablet form but may be in the form of an injection, liquid, patches or infusion.

Before being discharged from any trial, it is mandatory that you attend post-trial blood tests and a medical examination. Then, usually two days following this examination, you are paid for having helped us.

At Simbec we aim to make your stay as comfortable as possible with a full range of free facilities available. Examples are satellite TV, PlayStation consoles, daily newspapers and board & trivia games. There are also pool tables for your use. If you want to study or just unwind, there is a quiet room with free Internet access on hand for you. There is also Wifi access on each ward if you wish to bring your laptop. We provide you with all your meals during your stay at Simbec, although there may be certain restrictions on what you can eat. We can, upon request, provide alternative dietary plans, such as vegetarian meals where the study requirements allow it.

Am I eligible to take part?

We are looking for regular healthy men and women like you.

Each year, we have in excess of 1000 individuals who take part in our trials, including people from professional backgrounds, students, factory workers, housewives and retired men & woman.

If you wish to apply IT IS IMPORTANT that you go through the checklist to see if you are suitable to join our panel. If suitable, please confirm the documents you will need to bring with you for your first visit.

Give us a call

Simply contact one of our recruitment staff who will be happy to take you through the initial process of joining our panel of volunteers.

0800 691995


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